Brooks Women's Adrenaline GTS 22 Running Shoes Sleek and supportive design. Ideal for running and workouts. Lightweight and breathable. THIS WOMEN'S SHOE IS FOR: Runners looking for a smooth ride, with great cushion and trusted GuideRails support that won't distract from the fun of the run. This Brooks Adrenaline GTS 22 is a certified PDAC A5500 Diabetic shoe and has been granted the APMA Seal of Acceptance. It is recommended to size up 1/2 to one size larger than your dress shoe. A lot of tread left and plenty more running miles.